Diffusion weighted imaging in prostate cancer

Signal Intensity of High B-value Diffusion-weighted Imaging for the Detection of Prostate Cancer

Background: Diffusion-weighted imaging (DWI) is a main component of multiparametric MRI for prostate cancer detection. Recently, high b value DWI has gained more attention because of its capability for tumor characterization. Objective: To assess based on histopathological findings of transrectal ultrasound (TRUS)-guided prostate biopsy as a reference, an...

High-Resolution Diffusion-weighted Imaging Increases Prostate Cancer Visibility?

Article history: Received 13 April 2016 Accepted 13 April 2016 Available online 16 April 2016 Gleason score of tumors found with transrectal ultrasound compared to radical prostatectomy (ranging from 30 to 50%, depending on initial Gleason score) (Pinthus et al., 2006; Corcoran et al., 2011). This highresolution technique may further improve lesion characterization and ultimately be used to per...

Investigation of prostate cancer using diffusion weighted IVIM imaging

Introduction: Diffusion-weighted Imaging (DWI) and the derived apparent diffusion coefficient (ADC) were reported by several groups [1,2] to differentiate cancerous and healthy tissue in the prostate. The Intravoxel Incoherent Motion (IVIM) Theory, which predicts an additional component in the signal equation due to perfusion [3], could recently be applied to the liver and the pancreas [4,5]. F...

Computed diffusion-weighted MRI in prostate cancer

Diffusion Kurtosis Imaging in Prostate Cancer

Introduction: Diffusion weighted imaging (DWI) and the calculated apparent diffusion coefficient (ADC) is showing potential for improving detection of prostate cancer (PCa), as the increased cellularity of many tumors is associated with restricted water diffusion and thus with a decreased ADC [1,2]. The ADC assumes Gaussian water diffusion and is calculated by monoexponential fitting. However, ...